HGH Fragment 176-191 Peptide

International Peptides

Scientists are increasingly looking at ways to assist in the treatment of obesity and overweight, due to the alarming rate at which the prevalence of these conditions is growing. This has led to research being conducted on certain peptides, which include specific amino acid chains, to assist in reducing fat mass in the human body.

HGH Fragment 176-191 has become a popular research subject. In addition to providing positive results in laboratory tests that included rats and other animals, studies have also shown that the peptide holds the potential to assist in the treatment of excess weight in human subjects as well.

What Is HGH Fragment 176-191?

HGH Fragment 176-191, sometimes also just called HGH Frag 176-191, is a synthetically modified version of existing amino acids. The specific amino acids that are included in this modification include the 176-191 amino acids that are fragments of the Growth Hormone polypeptide. For those who would like to get more technical, HGH Fragment 176-191 is classified as a 15-mer peptide. It is also just a fragment of the C-terminus that forms part of the human growth hormone, a hormone that has a large role to play in human development, growth, and even fat distribution.

The peptide was first discovered by researchers at the Monash University. They found that the ability of Growth Hormone to reduce fat in the body seems to be linked to a single area that sits at the end of the hormone’s molecule. This is the 176-191 fragment, of course. The specific fragment discovered was almost 10% the size of an entire Growth Hormone.

After further research, a major discovery was made. While Growth Hormone itself has an effect on insulin secretion and growth in the body, this particular fragment did not seem to exert similar effects. Instead, it only seemed to work on reducing fat content in the body.

How Does HGH Fragment 176-191 Work?

The HGH Fragment 176-191 peptide seems to work in two different ways in order to achieve the desired results – which is a reduction of fat, providing potentially suitable treatment for obese patients.

First, the peptide seems to effectively stimulate a process in the body known as lipolysis. This process refers to the breakdown of fat, as well as the destruction of the fat cells in the body. One study1 did confirm that molecules that form part of Growth Hormone can effectively activate this particular process and lead to improved metabolism, along with reductions in fat mass within the subject’s body.

Furthermore, HGH Fragment 176-191 also seems to inhibit a process known as lipogenesis. This process causes foods that do not contain fat to be converted into fat and then stored within the body. This is a major cause of weight gain in the general population. Thus, by effectively inhibiting the function and activation of the lipogenesis process, the HGH Fragment 176-191 may further assist in the treatment of obesity and overweight by reducing the risk of further weight gain in the patient.

The combination of preventing further weight gain and causing the destruction of existing fat cells is primarily how the peptide works to provide improvements in weight management and, in some cases, relatively fast weight loss, especially among patients with larger amounts of body fat.

HGH Fragment 176-191 Side-Effects

Even though HGH Fragment 176-191 is generally considered to be a safe option for individuals who are trying to lose weight, it is important to realize that some potential side-effects have been noted in studies. While initial research revealed that the HGH fragment does not cause any significant changes in insulin levels, we did find one study2 that provided evidence of an alteration in both blood glucose levels and plasma insulin. These results were noted with the use of the HGH Fragment 176-191 in particular. The effects were short-lived, however, which means they did not last for a significant period of time.

HGH Fragment 176-191 Dosage in a controlled research environment

The dosage of HGH Fragment 176-191 depends from person to person, but tend to vary from around 250mcg on a daily basis up to 500mcg. The maximum recommended daily dosage is 500mcg. The peptide can be administered up to two times each day. The first injection should be administered in the morning and the second prior to the patient going to bed. For best results, it is advised that the peptide is administered on an empty stomach.

Where To Buy HGH Fragment 176-191?

At the moment, many patients interested in using HGH Fragment 176-191 might find it difficult to get their hands on the peptide. The majority of suppliers who do offer the peptide at the moment only provides it for research purposes and clearly states that the product is not for human consumption.

There are, however, a few retailers that do stock the product in a form that is appropriate for human subjects. It is crucial for a patient to conduct thorough research before deciding on a supplier to buy HGH Fragment 176-191 peptides from. The purity of the peptide needs to be high in order for it to work effectively and to avoid potential risks and side-effects.


The use of HGH Fragment 176-191 peptides, a small amino acid chain that is part of Growth Hormone in the human body, may yield positive effects in terms of treating patients who are obese or overweight. Studies have confirmed that the peptide can effectively stimulate processes in the body that may destroy existing fat cells and prevent a further accumulation of fat.


1 M. Heffernan, R.J. Summers, A. Thorburn, E. Ogru, R. Gianello, W.J. Jiang, F.M. Ng. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Journal of Endocrinology. Dec 2001. https://www.ncbi.nlm.nih.gov/pubmed/11713213

2 F.M. Nq, J. Bornstein. Hyperglycemic action of synthetic C-terminal fragments of human growth hormone. The American Journal of Physiology. May 1978. https://www.ncbi.nlm.nih.gov/pubmed/645904

For educational/research purposes only. This is not medical advice.

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