Sermorelin Acetate Peptide

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Hormones play key roles in the human body and interact with all cells in order to produce specific functions. Unfortunately, the aging body is prone to experience a reduction in the secretion of crucial hormones. One important hormone that is known to affect the body with age is human growth hormone, a hormone that is responsible for the well-being of bones, muscle tissue, and many other parts of the body. With age, the production of human growth hormone declines, and this can cause a series of problems in the body.

There are different solutions that men can opt for when their levels of human growth hormone start to decline, such as injections that contain synthetic HGH hormones. Not everyone responds well to such treatments, however, as side-effects often tend to develop. Alternatives are available – such as peptide treatment with Sermorelin Acetate Peptide, a hormone that is known to help increase the level of human growth hormone in the body and yield several useful benefits.

What Is Sermorelin Acetate?

Sermorelin Acetate, a peptide that is often referred to as GRF 1-29, is a combination of 29 amino acids. The combination is classified as a Growth Hormone Releasing Hormone or abbreviated as a GHRH. The purpose of this peptide, or sometimes referred to as a hormone, is to stimulant a specific gland, known as the pituitary gland, in order to cause an increase in the production of human growth hormone.

The peptide does not introduce the body to exogenous hormones like some other treatments do, but rather helps the body naturally produce more of this crucial hormone that is needed for muscle growth and strength, bone health, and other important functions in the body.

It should be noted that the body already contains Sermorelin naturally. These peptides are created when specific amino acids combine and are used to stimulate the pituitary gland to ensure adequate levels of human growth hormone can be released. When used in a medical setting, however, Sermorelin has synthetically produced form a specific combination of amino acids in order to produce a similar effect to the natural peptide that is found in the human body. In these cases, the peptide is called Sermorelin Acetate and consists of acetate salt of the synthetic amino acid combination1.

The use of Sermorelin in the treatment of human growth hormone deficiency is considered beneficial and a safer approach compared to some of the other conventional methods that are available for men. This is why an increasing number of physicians specializing in age-related conditions and medicines that focuses on the longevity of their patients are turning to the peptide to treat deficiencies in human growth hormone among their patients.

Sermorelin Acetate Benefits

Sermorelin Acetate has been associated with a great number of benefits in men who are experiencing a reduction in the level of growth hormone present in their body. Below is a list of potential benefits that men may experience when they are treated with this peptide2:

  • Growth Hormone production is naturally increased.
  • With a natural increase in Growth Hormone production, levels of IGF-1 also increases.
  • Immune function is enhanced.
  • The heart becomes stronger and healthier.
  • Energy levels are elevated, and overall vitality is boosted.
  • Lean muscle development happens faster and easier than before.
  • A process of lipolysis occurs, reducing fat storage in the body.
  • Wound healing is greatly accelerated.
  • Bone density is improved, along with the body’s ability to retain calcium.
  • Sleep quality is improved, and patients who experience insomnia may find that they are able to sleep better.
  • The mental function may also benefit from the use of this peptide.

Sermorelin Acetate Side Effects

In most men, when an appropriate dose of Sermorelin is administered, the peptide will be generally safe and should not lead to any serious side-effects. There are, however, cases where a patient may experience some adverse reactions when they use this peptide as a treatment for a Growth Hormone Deficiency.

Some of the possible side-effects that may occur in men who are injected with a solution containing Sermorelin Acetate include3:

  • Headaches
  • Dizziness
  • Tiredness
  • Hyperactivity
  • Flushing
  • Pale skin
  • A tight feeling in their chest
  • Swallowing difficulties
  • Nausea and vomiting
  • Hives

In some cases, the patient may also experience a reaction at the site where the injection is made. This can include swelling, redness, and possibly pain.

HGH Vs. Sermorelin

Sermorelin Acetate holds a number of potential benefits over a treatment option such as using exogenous human growth hormones to assist with a deficiency in the hormone among male patients. The major advantage is the fact that Sermorelin Acetate does not use any type of Growth Hormones from exogenous sources, but rather stimulates the release of more Growth Hormone in the body.

With the administration of synthetic Growth Hormone from exogenous sources, it becomes difficult to control how much of the hormone is introduced to the body. When tissue in the patient’s body is exposed to exogenous hormones, side-effects may also occur. Furthermore, it is also known that the use of Sermorelin can help to reduce the rate at which the body naturally reduces the production of Growth Hormone.


Sermorelin Acetate, a synthetic peptide that consists of multiple amino acids, have shown promising results when it comes to elevating levels of human growth hormone in the human body. The use of Sermorelin therapy can help men who experience adverse effects due to a decline in hormone production possibly reverse these symptoms. Some men may also find that their physical performance improves significantly with the use of this peptide, strength is boosted, and their overall health is greatly enhanced.


1 Sermorelin. PubChem Open Chemistry Database.

2 M. Hunsinger. Peptide therapy benefits – what is sermorelin. TeleWellnessMD. 14 Sep 2017.

3 J.P. Cunha. Sermorelin Acetate. 25 Oct 2016.

For educational/research purposes only. This is not medical advice.

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