The word SARM stands for “Selective Androgen Receptor Modulator,” and just like the other selective receptor modulators, SARMS can either block, or stimulate, the same nuclear hormone receptors under different conditions. Consequently, if it can block or stimulate a receptor in a tissue selective manner, it may be able to mimic the beneficial effects in one tissue. And, at the same time, minimize the unwanted effects of the synthetic steroidal hormones in other tissues. Since SARMS are a class of androgens (a specific class of hormones that serve as ligands), they can bind to cellular androgen receptors. As a result, the androgen receptors will trigger a complex signal transduction pathway that will lead to a greater expression of specific genes.

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